Madame Yes is a character on the Flintstone Cartoon Series
In the Cartoon series she appears in the Fifth Season episode "Doctor Sinister" as a mysterious Lady Spy who gets the gullible Fred and Barney into trouble but always vanishes when they need her the most!
- Barney actually begs Doctor Sinister to save him and Fred from "Madame Yes"!
- She reappears in the Cartoon Movie "A Man called Flintstone" as the female accomplice "Tanya" of the villionoius "Green Goose". However she ends up with the Green Goose and their 2 hencehmen last seen being shot off into Outer space.